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It is not a licensed medicine, is not approved for human or veterinary use, and must not be administered to any living organism outside a formally approved research protocol
Consistent with this, the expressions of the oligodendrocytic lactate transporter monocarboxylate transporter 1 (SLC16A1) was decreased in the spinal cords of patients with ALS and SOD1 G93A mice (Lee et al., 2012
Spermidine-mediated induction of autophagy requires that the pro-autophagic transcription factor identified as TFEB (transcription factor EB, where the EB refers to enhancer box binding site) be activated
It allows glutathione in cells to remain in its active, reduced state
& He, W
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